BDBM50014846 (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide::(S)-colchicine::7alphaH-colchicine::CHEMBL107::COLCHICINE::N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide::colchicina::colchicinum
SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC
InChI Key InChIKey=IAKHMKGGTNLKSZ-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50014846
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of purified bovine brain tubulin polymerisation in the absence of microtubule-associated proteins.More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of tubulin polymerization activity using homogenous bovine brain tubulin at 45 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of tubulin polymerization activity using homogenous bovine brain tubulin at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of tubulin polymerization activity using homogenous bovine brain tubulin at 37 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Compound was evaluated for inhibition of tubulin polymerization using purified bovine brain tubulin, activity expressed as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of tubulin polymerization with preincubation for 15 minutes at 37 degree Centigrade prior to addition of the GTP required for polymerizati...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of tubulin polymerization using isolated calf brain at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization using isolated calf brain at 26 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 sec for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Tubulin polymerization by a 40 uM solution of compound; compound showed inhibition >50% at 40 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Tested for inhibition against tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine brain tubulin polymerization (ITP).More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 secs for 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins in presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair